PITTSBURGH — Senorise Perry rushed for 101 yards and a career-high four touchdowns to help No. 18 Louisville race by Pittsburgh 45-35 on Saturday.
Teddy Bridgewater passed for 304 yards for the Cardinals (6-0, 1-0 Big East), including a 75-yard score to Devante Parker on the first play of the second half as Louisville continued its best start since 2006.
Parker's score came in the middle of a 24-point burst by Louisville spanning the second and third quarters that turned a seven-point deficit into a 38-21 lead.
Tino Sunseri passed for 287 yards and two touchdowns but Pitt (2-4, 0-3) couldn't complete a late rally.
Trailing by 10 with 5 minutes to play, Pitt went for it on fourth down deep in Louisville territory rather than attempt a field goal. Sunseri's pass was off the mark and Perry finished off the Panthers with a 59-yard sprint down the left sideline.
ST. LOUIS — Eddie Lacy and T.J. Yeldon gave top-ranked Alabama a pair of 100-yard rushers in the same game for the first time this season and the duo combined for five scores in a soggy, weather-delayed victory over Missouri.
The defending national champion Crimson Tide (6-0, 3-0 SEC) led 21-0 late in the first quarter en route to their 10th straight victory, all by 19 or more points.
They did just enough right after that to disappoint the few thousand fans who didn't leave for good during a 38-minute delay due to lightning with the Crimson Tide awaiting the extra-point kick for a 28-0 cushion after Yeldon's second scoring run with 8:40 to go in the half.
BATON ROUGE, La. — LSU freshman Jeremy Hill highlighted a breakout 124-yard, two-touchdown performance with a 50-yard scoring run, and the ninth-ranked Tigers handed No. 3 South Carolina its first loss of the season, 23-21 on Saturday night.
LSU (6-1, 2-1 Southeastern Conference) substantially outgained South Carolina (6-1, 4-1) 406 yards to 211, but struggled to find the end zone. Three times, LSU settled for field goals after driving at least as far as the Gamecocks 5-yard line, and another drive to the South Carolina 15 stalled on a missed field goal.
NASHVILLE, Tenn. — Quarterback Jeff Driskel ran for 177 yards and three touchdowns, and fourth-ranked Florida beat Vanderbilt to remain undefeated going into the Gators' big showdown with No. 3 South Carolina.
The Gators (6-0, 5-0 SEC) finished off their last SEC road trip outside of the state of Florida with their 22nd straight win over Vanderbilt.
Florida, which rallied in the second half to beat Texas A&M, Tennessee and LSU already this season, took control early this time. The Gators scored 21 straight points, including 11 in the second quarter where they took the lead for good.
Vanderbilt (2-4, 1-3) now has lost 47 straight against Top Five teams.
LUBBOCK, Texas — Seth Doege passed for six touchdowns and a season-high 499 yards as Texas Tech shocked No. 5 West Virginia, ending the Mountaineers' hopes for an unbeaten season.
The Red Raiders fans stormed the field after the win, the most lopsided Texas Tech victory ever over a team ranked in the top five.
Texas Tech's defense consistently stymied West Virginia's offense. Heisman Trophy hopeful Geno Smith completed 29 of 55 passes for 275 yards.
The Red Raiders offense had no trouble moving the ball as Doege threw TD passes of 39, 19, 16, 2, 29 and 7 yards.
He completed 32 of 42 passes and the six touchdowns matched his career-high. Darrin Moore caught three touchdown passes.
AMES, Iowa — Quarterback Collin Klein ran for 105 yards and three touchdowns and sixth-ranked Kansas State held off Iowa State for its fifth straight win over the Cyclones.
Klein also threw for 187 yards for the Wildcats (6-0, 3-0 Big 12), who remain unbeaten heading into next week's showdown with West Virginia.
PROVO, Utah — Cody Vaz passed for 332 yards and three touchdowns in his first start since high school and No. 10 Oregon State used a strong start and bigger finish to beat Brigham Young.
Vaz was filling in for Sean Mannion, who is out indefinitely with a left knee injury.
Markus Wheaton caught two first-quarter TD passes, and scored on a 12-yard reverse in the fourth, while cornerback Jordan Poyer returned an interception 49 yards to seal the victory against BYU (4-3).
SEATTLE — Anthony Brown blocked a punt and returned it 21 yards for a touchdown in the first half, Jawanza Starling forced and recovered Keith Price's fumble inside the USC 5-yard line in the fourth quarter, and the No. 11 Trojans overcame offensive inconsistency for a 24-14 win over Washington on Saturday night.
Silas Redd rushed for 108 yards and a touchdown in the first half and Matt Barkley added an 18-yard TD pass to Xavier Grimble as the Trojans continued rebuilding their resume following last month's loss to Stanford that appeared to end their national championship hopes.
TALLAHASSEE, Fla. — EJ Manuel threw for a career-high 439 yards and four touchdowns and kicker Dustin Hopkins became the ACC's career scoring leader as 12th-ranked Florida State rebounded from its first loss of the season.
Manuel completed 27 of 34 passes before leaving early in the fourth quarter with a 48-7 lead.
DALLAS — Damien Williams broke off a 95-yard touchdown run for the longest rush in Red River Rivalry history, Blake Bell powered his way in for four TDs and No. 13 Oklahoma beat No. 15 Texas its second straight blowout in the series.
Landry Jones threw for 321 yards and two touchdowns, and fullback Trey Millard had a career-best 119 yards receiving as the Sooners (4-1, 2-1 Big 12) added another rout to Bob Stoops' impressive rivalry resume.
PISCATAWAY, N.J. — Duron Harmon scooped up a blocked field goal attempt and ran 75 yard for a tie-breaking touchdown early in the third quarter and No. 20 Rutgers rode its defense and special teams to victory.
Big East Conference defensive player of the year Khaseem Greene forced three fumbles and intercepted a pass as Rutgers (6-0, 3-0) became bowl eligible for the seventh time in eight seasons.
CINCINNATI — Deven Drane scooted 76 yards for a touchdown after picking up a fumble and Munchie Legaux threw two TD passes including a 78-yarder to Travis Kelce to lead No. 21 Cincinnati past Fordham 49-17 on Saturday night.
The Bearcats (5-0) stayed perfect but the Rams (4-3), playing up a level from the Football Championship Subdivision, hung around for a half. The win was Cincinnati's 24th straight in nonconference games at Nippert Stadium.
BOISE, Idaho — D.J. Harper rushed for 122 yards and a touchdown and Joe Southwick threw for another score to lead No. 24 Boise State over Fresno State.
Harper was the leader of a Boise State (5-1, 2-0 Mountain West) rushing attack that chewed up 215 yards on the ground and propelled the Broncos to their seventh straight victory over the Bulldogs.