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By JAY COHEN

CHICAGO (AP) — Yasmani Grandal homered twice and drove in eight runs in his return from the injured list, and the Chicago White Sox beat the sloppy Chicago Cubs 17-13 on Friday night.

The eight RBIs for Grandal matched the franchise record and the career best for the switch-hitting catcher. He also doubled and singled.

José Abreu added three hits and two RBIs as the White Sox improved to an AL-best 43-23 at home this year. Luis Robert also had three hits and scored three times, and Yoán Moncada extended his hitting streak to 13 games.

The AL Central-leading White Sox improved to 4-0 against the crosstown Cubs, winning the season series for the first time since 2014.

The fourth-place Cubs scored six times in the first against Dallas Keuchel, but they couldn’t hold on against the powerful White Sox lineup. Patrick Wisdom homered twice and drove in four runs for the North Siders on his 30th birthday, and Michael Hermosillo hit a solo shot to go along with two impressive catches in center field.

Wisdom and Ian Happ connected in the ninth against former Cubs closer Craig Kimbrel before he fanned Austin Romine for the final out.

The 32-year-old Grandal had an immediate impact in his first game with the White Sox since he tore a tendon in his left knee July 5 at Minnesota.

He connected for his 15th homer in the third, tying it at 6 with a towering three-run drive to right against Keegan Thompson in the rookie right-hander’s third big league start.

With two out and runners on first and second, Robert hit a popup against Adrian Sampson (0-1) that shortstop Andrew Romine dropped for his second error of the inning. Andrew Vaughn scored to give the White Sox a 7-6 lead, and Eloy Jiménez capped the eight-run rally with a two-run single.

Grandal added a two-run double in the fifth, a single in the seventh and another three-run shot in the eighth. He also threw out Frank Schwindel attempting to steal second in the second.

The successful return for Grandal overshadowed another rough outing for Keuchel, who was tagged for six runs, five earned, and seven hits. The left-hander was pulled by manager Tony La Russa after he threw one pitch to Wisdom with a runner on first and none out in the second.

Reynaldo López (3-1) came in and pitched five perfect innings, striking out seven.

Since winning consecutive starts against Toronto and Tampa Bay in June, Keuchel is 2-6 with a 6.67 ERA in 12 games.

IT HAPPENED BEFORE

The Cubs jumped out to a 7-0 lead in the first inning at Milwaukee on June 30 — and lost 15-7. It was part of an 11-game slide that sent the team spiraling out of contention.

TRAINER’S ROOM

Cubs: INF David Bote was scratched after he sprained his right ankle during batting practice when he stepped on a baseball obscured by some white lettering in foul territory at Guaranteed Rate Field. … Manager David Ross said C Willson Contreras (sprained right knee) likely will head out on a rehab assignment soon. “I think he wants a couple at-bats,” Ross said. … RHP Adbert Alzolay (left hamstring strain) felt fine after pitching two innings in a rehab start with Triple-A Iowa on Wednesday. “We’ll get him back soon,” Ross said.

UP NEXT

Right-handers Alec Mills (5-6, 4.65 ERA) and Lance Lynn (10-3, 2.20 ERA) pitch on Saturday. Mills has dropped his last two starts for the Cubs, allowing nine runs and 19 hits in 9 2/3 innings. Lynn is looking for his first win since July 25, posting a 3.33 ERA during a stretch of five straight no-decisions for the White Sox.

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Jay Cohen can be reached at https://twitter.com/jcohenap

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